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Anti-ROR1 monoclonal antibody   (CABT-34798MH)  


Mouse anti-Human ROR1 monoclonal antibody for ELISA, ICC/IF, WB           Datasheet

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Specifications
Host Species
Mouse
Antibody Isotype
IgG1
Clone
3I7
Species Reactivity
Human
Immunogen
Recombinant fragment, corresponding to extracellular amino acids 30-406 of Human ROR1 fused with hIgGFc tag, expressed in HEK293 cells.
Conjugate
Unconjugated
Applications
Application Notes
Flow Cyt: 2μg/106 cells; WB: 1/500 - 1/2000; ELISA: 1/10000; ICC/IF: 1/200 - 1/1000.

*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target
Alternative Names
ROR1; receptor tyrosine kinase-like orphan receptor 1; NTRKR1; tyrosine-protein kinase transmembrane receptor ROR1; dJ537F10.1; receptor-related 1; MGC99659; Neurotrophic tyrosine kinase; Neurotrophic tyrosine kinase receptor related 1; Neurotrophic tyros
Entrez Gene ID
4919
UniProt ID
Q01973
Product Background
Pathway
Nuclear Receptors, organism-specific biosystem;
References
Hojjat-Farsangi, M; Mozaffari, F; et al. Patients with Chronic Lymphocyte Leukemia (CLL) Have Naturally Occurring Antibodies Against the Receptor Tyrosine Kinase (ROR1). BLOOD 118:773-773(2011).
Lapalombella, R; Andritsos, L; et al. Lenalidomide treatment promotes CD154 expression on CLL cells and enhances production of antibodies by normal B cells through a PI3-kinase-dependent pathway. BLOOD 115:2619-2629(2010).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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United States
Tel: 1-631-624-4882
Fax: 1-631-938-8221
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Tel: 44-207-048-3343
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