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Anti-NOX4 monoclonal antibody   (CABT-38500RH)  


Rabbit anti-Human NOX4 monoclonal antibody for WB, IP, IHC-P, ICC           Datasheet

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Specifications
Host Species
Rabbit
Antibody Isotype
IgG1
Clone
FQ3840Z
Species Reactivity
Mouse, Rat, Dog, Human
Immunogen
A synthetic peptide corresponding to residues in Human NOX4
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/2000; IP: 1/30; IHC-P: 1/250 - 1/500; ICC: 1/200.

*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target
Alternative Names
NOX4; NADPH oxidase 4; KOX; KOX 1; Kidney oxidase-1; Kidney superoxide-producing NADPH oxidase; KOX 1; KOX; Kox-1; NADPH oxidase 4; Nox4; NOX4_HUMAN; Renal NAD(P)H-oxidase; RENOX; kidney oxidase-1; renal NAD(P)H-oxidase; kidney superoxide-producing NADPH
Entrez Gene ID
50507
UniProt ID
Q9NPH5
Product Background
Pathway
Oxidative Stress, organism-specific biosystem; Signaling events mediated by PTP1B, organism-specific biosystem;
References
Thum, T; Borlak, J; et al. Mechanistic role of cytochrome P450 monooxygenases in oxidized low-density lipoprotein-induced vascular injury - Therapy through LOX-1 receptor antagonism?. CIRCULATION RESEARCH 94:E1-E13(2004).
Boudreau, HE; Emerson, SU; et al. Hepatitis C Virus (HCV) Proteins Induce NADPH Oxidase 4 Expression in a Transforming Growth Factor beta-Dependent Manner: a New Contributor to HCV-Induced Oxidative Stress. JOURNAL OF VIROLOGY 83:12934-12946(2009).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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United States
Tel: 1-631-624-4882
Fax: 1-631-938-8221
Europe
Tel: 44-207-048-3343
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