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Anti-LCAT monoclonal antibody   (CABT-38705RH)  


Rabbit anti-Human LCAT monoclonal antibody for ICC, WB, IP, IHC-P           Datasheet

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Specifications
Host Species
Rabbit
Antibody Isotype
IgG1
Clone
e26
Species Reactivity
Mouse, Rat, Human
Immunogen
Synthetic peptide corresponding to residues in Human LCAT.
Conjugate
Unconjugated
Applications
Application Notes
ICC: 1/100 - 1/250; WB: 1/1000 - 1/10000; IP: 1/10 - 1/100; IHC-P: 1/250 - 1/500;

*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target
Alternative Names
LCAT; lecithin-cholesterol acyltransferase; phosphatidylcholine-sterol acyltransferase; LCAT; LCAT_HUMAN; Lecithin cholesterol acyltransferase; Lecithin-cholesterol acyltransferase; Phosphatidylcholine sterol acyltransferase; Phosphatidylcholine-sterol ac
Entrez Gene ID
3931
UniProt ID
P04180
Product Background
Pathway
Glycerophospholipid metabolism, organism-specific biosystem; Glycerophospholipid metabolism, conserved biosystem; HDL-mediated lipid transport, organism-specific biosystem; Lipid digestion, mobilization, and transport, organism-specific biosystem; Lipoprotein metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Statin Pathway, organism-specific biosystem;
References
Kwong, M; Sivak, O; et al. Cyclosporine A transfer between high- and low-density lipoproteins: Independent from lipid transfer protein I-facilitated transfer of lipoprotein-coated phospholipids because of high affinity of cyclosporine A for the protein component of lipoproteins. JOURNAL OF PHARMACEUTICAL SCIENCES 90:1308-1317(2001).
Jimi, S; Uesugi, N; et al. Possible induction of renal dysfunction in patients with lecithin : cholesterol acyltransferase deficiency by oxidized phosphatidylcholine in glomeruli. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 19:794-801(1999).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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United States
Tel: 1-631-624-4882
Fax: 1-631-938-8221
Europe
Tel: 44-207-048-3343
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