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Anti-Interleukin-12/-23 monoclonal antibody   (DMAB8015)  


Mouse anti-Human Interleukin-12/-23 monoclonal antibody for ELISA, ELISPOT           Datasheet

Specifications
Host Species
Mouse
Antibody Isotype
IgG1
Clone
NU619
Species Reactivity
Human
Immunogen
Recombinant human IL-23
Conjugate
Unconjugated
Target
Alternative Names
Il12b; interleukin 12b; p40; Il-12b; Il12p40; Il-12p40; interleukin-12 subunit beta; CLMF p40; IL-12 p40; IL-12 subunit p40; IL-23 subunit p40; cytotoxic lymphocyte maturation factor 40 kDa subunit; Il23a; interleukin 23, alpha subunit p19; p19; IL-23; in
References
Tillack, C; Ehmann, LM; et al. Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-gamma-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment. GUT 63:567-577(2014).
Brand, S; et al. Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease. GUT 58:1152-1167(2009).

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