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Anti-IGF1R monoclonal antibody   (CABT-29810MH)  


Mouse anti-Human IGF1R monoclonal antibody for WB           Datasheet

Specifications
Host Species
Mouse
Antibody Isotype
IgG1
Clone
3D9
Species Reactivity
Human
Immunogen
Purified human placental IGF-1 receptors.
Conjugate
Unconjugated
Target
Alternative Names
IGF1R; insulin-like growth factor 1 receptor; CD221; IGFIR; IGFR; JTK13; MGC18216; CD221; CD221 antigen; IGF I receptor; IGFIR; Insulin like growth factor I receptor; JTK13; IGF-I receptor; OTTHUMP00000194784; soluble IGF1R variant 1; soluble IGF1R varian
Entrez Gene ID
3480
UniProt ID
P08069
Product Background
Pathway
Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Apoptosis, organism-specific biosystem; Endochondral Ossification, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; Glioma, organism-specific biosystem; Glioma, conserved biosystem; IGF1 pathway, organism-specific biosystem; Id S
References
Tworkoski, K; Raab-Traub, N; et al. LMP1 Promotes Expression of Insulin-Like Growth Factor 1 (IGF1) To Selectively Activate IGF1 Receptor and Drive Cell Proliferation. JOURNAL OF VIROLOGY 89:2590-2602(2015).
Puzanov, I; Lindsay, CR; et al. A Phase I Study of Continuous Oral Dosing of OSI-906, a Dual Inhibitor of Insulin-Like Growth Factor-1 and Insulin Receptors, in Patients with Advanced Solid Tumors. CLINICAL CANCER RESEARCH 21:701-711(2015).

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Tel: 1-631-624-4882
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Tel: 44-207-048-3343
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