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Anti-HBEGF monoclonal antibody   (CABT-30085MH)  


Mouse anti-Human HBEGF monoclonal antibody for ICC/IF, IP, WB           Datasheet

Specifications
Host Species
Mouse
Antibody Isotype
IgG1
Clone
5H20
Species Reactivity
Human
Immunogen
Recombinant human HB EGF ectodomain expressed in SF21 cells.
Conjugate
Unconjugated
Applications
Application Notes
WB: 0.2 - 1 μg/ml; ICC/IF: 5 - 10 μg/ml.

*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target
Alternative Names
HBEGF; heparin-binding EGF-like growth factor; diphtheria toxin receptor (heparin binding epidermal growth factor like growth factor) , DTR, DTS, HEGFL; proheparin-binding EGF-like growth factor; Diphtheria toxin receptor (heparin binding EGF like growth
Entrez Gene ID
1839
UniProt ID
Q99075
Product Background
Pathway
Epithelial cell signaling in Helicobacter pylori infection, organism-specific biosystem; Epithelial cell signaling in Helicobacter pylori infection, conserved biosystem; ErbB receptor signaling network, organism-specific biosystem; ErbB signaling pathway, organism-specific biosystem; ErbB signaling pathway, organism-specific biosystem; ErbB signaling pathway, conserved biosystem; ErbB4 signaling events, organism-specific biosystem; GnRH signaling pathway, organism-specific biosystem; GnRH signal
References
Rigo, A; Gottardi, M; et al. Macrophages may promote cancer growth via a GM-CSF/HB-EGF paracrine loop that is enhanced by CXCL12. MOLECULAR CANCER 9:-(2010).
Wu, WD; Samet, JM; et al. Heparin-binding epidermal growth factor cleavage mediates zinc-induced epidermal growth factor receptor phosphorylation. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 30:540-547(2004).

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