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Anti-GAA polyclonal antibody   (CPBT-35311RH)  


Rabbit anti-Human GAA (full length) polyclonal antibody for WB           Datasheet

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Specifications
Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Mouse, Human
Immunogen
Full length protein, corresponding to amino acids 1-952 of Human GAA.
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/500 - 1/1000; IHC-P: 5μg/ml;

*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target
Alternative Names
GAA; glucosidase, alpha; acid; lysosomal alpha-glucosidase; glycogen storage disease type II; Pompe disease; 70 kDa lysosomal alpha-glucosidase; Acid alpha glucosidase; Acid maltase; Aglucosidase alfa; Alpha glucosidase; GAA; Glucosidase alpha acid (Pompe
Entrez Gene ID
2548
UniProt ID
P10253
Product Background
Pathway
Galactose metabolism, organism-specific biosystem; Galactose metabolism, conserved biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Metabolic pathways, organism-specific biosystem; Notch-mediated HES/HEY network, organism-specific biosystem; Starch and sucrose metabolism, organism-specific biosystem; Starch and sucrose metabolism, conserved biosystem;
References
Raben, N; Nagaraju, K; et al. Induction of tolerance to a recombinant human enzyme, acid alpha-glucosidase, in enzyme deficient knockout mice. TRANSGENIC RESEARCH 12:171-178(2003).
Nayak, S; Sivakumar, R; et al. Mapping the T helper cell response to acid alpha-glucosidase in Pompe mice. MOLECULAR GENETICS AND METABOLISM 106:189-195(2012).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
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United States
Tel: 1-631-624-4882
Fax: 1-631-938-8221
Europe
Tel: 44-207-097-1828
Email

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