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Anti-EGLN1 monoclonal antibody   (CABT-31311RH)  


Rabbit anti-Human EGLN1 monoclonal antibody for FC, ICC, IHC-P, IP, WB           Datasheet

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Specifications
Host Species
Rabbit
Antibody Isotype
IgG1
Clone
FQS4772
Species Reactivity
Mouse, Human
Immunogen
A synthetic peptide corresponding to C terminal residues of Human PHD2 / prolyl hydroxylase.
Conjugate
Unconjugated
Applications
Application Notes
ICC/IF: 1/200; WB: 1/1000 - 1/10000; IP: 1/10 - 1/100; IHC-P: 1/50 - 1/100; ICC: 1/100 - 1/250; Flow Cyt: 1/100;

*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target
Alternative Names
EGLN1; egl nine homolog 1 (C. elegans); C1orf12,EGL nine (C.elegans) homolog 1; egl nine homolog 1; HIF prolyl hydroxylase 2; HIFPH2; PHD2; SM 20; ZMYND6; Zinc finger MYND domain containing protein 6; C1ORF12; Chromosome 1 Open Reading Frame 12; DKFZp761F
Entrez Gene ID
54583
UniProt ID
Q9GZT9
Product Background
Pathway
HIF-1-alpha transcription factor network, organism-specific biosystem; HIF-2-alpha transcription factor network, organism-specific biosystem; Pathways in cancer, organism-specific biosystem; Renal cell carcinoma, organism-specific biosystem; Renal cell carcinoma, conserved biosystem;
References
Wolf, G; Schroeder, R; et al. Angiotensin II induces hypoxia-inducible factor-1 alpha in PC 12 cells through a posttranscriptional mechanism: Role of AT(2) receptors. AMERICAN JOURNAL OF NEPHROLOGY 24:415-421(2004).
Shen, C; Shao, ZY; et al. The Caenorhabditis elegans rhy-1 gene inhibits HIF-1 hypoxia-inducible factor activity in a negative feedback loop that does not include vhl-1. GENETICS 174:1205-1214(2006).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
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United States
Tel: 1-631-624-4882
Fax: 1-631-938-8221
Europe
Tel: 44-207-097-1828
Email

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