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Anti-CK-MM monoclonal antibody   (DMAB2205MH)  


Mouse anti-Human FGFR3 monoclonal antibody for WB, ELISA           Datasheet

Specifications
Host Species
Mouse
Antibody Isotype
IgG2b
Clone
A027-17186
Species Reactivity
Human
Immunogen
Purified human CK-MM
Conjugate
Unconjugated
Target
Alternative Names
CKMM; M-CK; CKM; creatine kinase M-type; creatine kinase-M; creatine kinase M chain
Entrez Gene ID
1158
UniProt ID
B2R892
Product Background
Antigen Description
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. The function about CK-MM antigen include ATP binding; creatine kinase activity; nucleotide binding.
Pathway
Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Creatine metabolism, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Regulation of retinoblastoma protein, organism-specific biosystem; Urea cycle and metabolism of amino groups, organism-specific biosystem; creatine-phosphate biosynthesis, conserved biosystem.
References
Guo, Z; Wang, Z; et al. Studies on the stability of creatine kinase isozymes. BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE 81:9-16(2003).
DIORIO, AF; HAMMER, P; et al. CARDIAC ISOENZYME (CK-MM ISOFORM) ASSAYS FOR EARLY DETECTION OF ACUTE MYOCARDIAL-INFARCTION - A COMPARISON OF IMMUNOMETRIC AND ELECTROPHORETIC SYSTEMS. CLINICAL CHEMISTRY 35:1117-1117(1989).

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Tel: 1-631-624-4882
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Tel: 44-207-048-3343
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