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Anti-CK-BB monoclonal antibody   (DMAB2204MH)  


Mouse anti-Human FGFR3 monoclonal antibody for WB, ELISA           Datasheet

Specifications
Host Species
Mouse
Antibody Isotype
IgG1
Clone
A027-11288
Species Reactivity
Human
Immunogen
Source: Human Brain
Conjugate
Unconjugated
Target
Alternative Names
B-CK; CKBB; CKB; creatine kinase B-type; creatine kinase-B; creatine kinase B chain
Entrez Gene ID
1152
UniProt ID
P12277
Product Background
Antigen Description
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. The function about CK-BB antigen include ATP binding; creatine kinase activity; nucleotide binding.
Pathway
Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Creatine metabolism, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Urea cycle and metabolism of amino groups, organism-specific biosystem; creatine-phosphate biosynthesis, conserved biosystem.
References
Arnold, H; Wienker, TF; et al. High levels of brain-type creatine kinase activity in human platelets and leukocytes: A genetic anomaly with autosomal dominant inheritance. BLOOD CELLS MOLECULES AND DISEASES 48:62-67(2012).
Parker, BA; Augeri, AL; et al. Effect of Statins on Creatine Kinase Levels Before and After a Marathon Run. AMERICAN JOURNAL OF CARDIOLOGY 109:282-287(2012).

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