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Anti-CFTR monoclonal antibody   (CABT-32594MH)  


Mouse anti-Human CFTR monoclonal antibody for FC, IHC-Fr, IHC-P           Datasheet

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Specifications
Host Species
Mouse
Antibody Isotype
IgG1
Clone
N4B8
Species Reactivity
Human
Immunogen
Recombinant protein encoding NBF 2 domain of human CFTR.
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 1/50 - 1/100;

*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target
Alternative Names
CFTR; cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7); ABCC7, CF,cystic fibrosis transmembrane conductance regulator, ATP binding cassette (sub family C, member 7); cystic fibrosis transmembrane conductanc
Entrez Gene ID
1080
UniProt ID
A0A024R730
Product Background
Pathway
ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; ABC-family proteins mediated transport, organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Gastric acid secretion, organism-specific biosystem; Gastric acid secretion, conserved biosystem; Pancreatic secretion, organism-specific biosystem; Pancreatic secretion, conserved biosystem; Transmembrane transport of small molecules, organism-specific biosystem
References
Hegedus, T; Aleksandrov, A; et al. Role of individual R domain phosphorylation sites in CFTR regulation by protein kinase A. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES 1788:1341-1349(2009).
Hinojosa-Kurtzberg, AM; Johansson, MEV; et al. Novel MUC1 splice variants contribute to mucin overexpression in CFTR-deficient mice. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 284:G853-G862(2003).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Tel: 1-631-624-4882
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United States
Tel: 1-631-624-4882
Fax: 1-631-938-8221
Europe
Tel: 44-207-048-3343
Email

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