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Anti-APP monoclonal antibody   (DMAB8182MH)  


Mouse Anti-Human APP monoclonal antibody for ELISA           Datasheet

Specifications
Host Species
Mouse
Antibody Isotype
IgG1
Clone
DB911D12
Species Reactivity
Human
Immunogen
The C-terminal amino acid sequence (MVGGVVIA) of human beta amyloid peptide 42, conjugated with KLH.
Conjugate
Unconjugated
Target
Alternative Names
APP; amyloid beta (A4) precursor protein; AAA; AD1; PN2; ABPP; APPI; A4; CVAP; ABETA; PN-II; CTFgamma; amyloid beta A4 protein; preA4; protease nexin-II; peptidase nexin-II; beta-amyloid peptide; alzheimer disease amyloid protein; cerebral vascular amyloi
Entrez Gene ID
351
UniProt ID
P05067
Product Background
Pathway
Activated TLR4 signalling; Advanced glycosylation endproduct receptor signaling; Alzheimer"s disease; Amyloids; Caspase cascade in apoptosis; Delta-Notch Signaling Pathway; GPCR downstream signaling; GPCR ligand binding; Glypican 1 network; Hemostasis; Im
References
Meulendyke, KA; Queen, SE; et al. Combination fluconazole/paroxetine treatment is neuroprotective despite ongoing neuroinflammation and viral replication in an SIV model of HIV neurological disease. JOURNAL OF NEUROVIROLOGY 20:591-602(2014).
Tozzi, A; Sclip, A; et al. Region- and age-dependent reductions of hippocampal long-term potentiation and NMDA to AMPA ratio in a genetic model of Alzheimer's disease. NEUROBIOLOGY OF AGING 36:123-133(2015).

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