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Anti-GAA monoclonal antibody   (DCABH-5015)  


Mouse anti-Human GAA monoclonal antibody for WB, IHC-P           Datasheet

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Specifications
Host Species
Mouse
Antibody Isotype
IgG1
Clone
54H8
Species Reactivity
Human
Immunogen
Purified Human GAA from Human placenta (NP_000143.2).
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 1/50.

*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target
Alternative Names
GAA; glucosidase, alpha; acid; lysosomal alpha-glucosidase; glycogen storage disease type II; Pompe disease; acid maltase; aglucosidase alfa; LYAG;
Entrez Gene ID
2548
UniProt ID
P10253
Product Background
Pathway
Galactose metabolism, organism-specific biosystem; Galactose metabolism, conserved biosystem; Lysosome, organism-specific biosystem; Lysosome, conserved biosystem; Metabolic pathways, organism-specific biosystem; Notch-mediated HES/HEY network, organism-specific biosystem; Starch and sucrose metabolism, organism-specific biosystem;
References
Han, SO; Li, ST; et al. Enhanced Efficacy from Gene Therapy in Pompe Disease Using Coreceptor Blockade. HUMAN GENE THERAPY 26:26-35(2015).
FREEMAN, J; SCHMIDT, S; et al. MUTATION OF CONSERVED DOMAIN-II ALTERS THE SEQUENCE SPECIFICITY OF DNA-BINDING BY THE P53 PROTEIN. EMBO JOURNAL 13:5393-5400(1994).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
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United States
Tel: 1-631-624-4882
Fax: 1-631-938-8221
Europe
Tel: 44-207-097-1828
Email

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