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Anti-ATPase p97 monoclonal antibody   (DMAB3012)  


Mouse anti-ATPase p97 monoclonal antibody for WB           Datasheet

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Specifications
Host Species
Mouse
Antibody Isotype
IgG1
Clone
A60.14.4
Species Reactivity
N/A
Immunogen
15S Mg2+ ATPase complex purified from Xenopus laevis ovary
Conjugate
Unconjugated
Target
Alternative Names
15S Mg(2+) ATPase p97 subunit; 15S Mg(2+)-ATPase p97 subunit; ATPase p97; IBMPFD; MGC131997; MGC148092; MGC8560; p97; TER ATPase; TERA; TERA_HUMAN; transitional endoplasmic reticulum ATPase; Valosin containing protein; valosin-containing protein; VCP; yea
Product Background
Antigen Description
Defects in VCP arethe cause of inclusion body myopathy with early-onset Paget disease andfrontotemporal dementia (IBMPFD) [MIM:167320]; also known as musculardystrophy, limb-girdle, with Paget disease of bone or pagetoid amyotrophiclateral sclerosis or pagetoid neuroskeletal syndrome or lower motor neurondegeneration with Paget-like bone disease. IBMPFD features adult-onsetproximal and distal muscle weakness (clinically resembling limb girdlemuscular dystrophy), early-onset Paget disease of bone in most cases andpremature frontotemporal dementia. Suitable for use in Western blot (1:1,000 – 1:2,000). Not for use in immunofluorescence and immunoprecipitation. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
References
Wei, H; Li, ZW; et al. microRNA-151-3p Regulates Slow Muscle Gene Expression by Targeting ATP2a2 in Skeletal Muscle Cells. JOURNAL OF CELLULAR PHYSIOLOGY 230:1003-1012(2015).
Meng, D; Bruschweiler-Li, L; et al. NMR backbone resonance assignments of the N, P domains of CopA, a copper-transporting ATPase, in the apo and ligand bound states. BIOMOLECULAR NMR ASSIGNMENTS 9:129-133(2015).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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United States
Tel: 1-631-624-4882
Fax: 1-631-938-8221
Europe
Tel: 44-207-097-1828
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