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Anti-14-3-3 monoclonal antibody   (DCABH-3890)  


Mouse anti-Human 14-3-3 monoclonal antibody for WB, IP           Datasheet

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Specifications
Host Species
Mouse
Antibody Isotype
IgG1
Clone
4G8
Species Reactivity
Human
Immunogen
Recombinant full length protein (Human 14-3-3 gamma).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 - 2 μg/ml;

*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target
Alternative Names
YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide; tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, alpha polypeptide , YWHAA; 14-3-3 protein beta/alpha; 14 3 3 alpha; 14 3 3 beta; 14-3-
Entrez Gene ID
7529
UniProt ID
P31946
Product Background
Pathway
ARMS-mediated activation, organism-specific biosystem; Activation of BAD and translocation to mitochondria, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Axon guidance, organism-specific biosystem;
References
Vancraenenbroeck, R; De Raeymaecker, J; et al. In silico, in vitro and cellular analysis with a kinome-wide inhibitor panel correlates cellular LRRK2 dephosphorylation to inhibitor activity on LRRK2. FRONTIERS IN MOLECULAR NEUROSCIENCE 7:-(2014).
Tsai, HC; Lee, BY; et al. Dexamethasone downregulated the expression of CSF 14-3-3 beta protein in mice with eosinophilic meningitis caused by Angiostrongylus cantonensis infection. ACTA TROPICA 131:98-103(2014).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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United States
Tel: 1-631-624-4882
Fax: 1-631-938-8221
Europe
Tel: 44-207-048-3343
Email

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